Company is developing a non-invasive system capable of delivering and activating particles that can deliver diverse payloads (heat, electricity, kinetic energy, drugs, cells and nucleic acids) anywhere in the head with high spatial resolution. The system starts with an MRI that has been modified to non-invasively deliver particles to specific locations under imaging guidance with millimeter resolution. The second part is the sterile single-use dose of magnetic payload-carrying bio-degradable particles that can be administered systemically or intra-nasally and concentrated magnetically to specific regions in the head.