Squamous cell carcinoma can recur if any cancer cells were left behind after treatment or if new cancer cells develop in the same area. Factors such as incomplete removal, aggressive tumor characteristics, and underlying genetic mutations may contribute to the recurrence of squamous cell carcinoma.
A more thorough response to your query
Squamous cell carcinoma, a type of skin cancer, can be aggressive and have the tendency to recur. The recurrence of this cancer may be attributed to several factors, such as incomplete removal of cancer cells during treatment, aggressive tumor characteristics, and underlying genetic mutations. Understanding why squamous cell carcinoma keeps coming back requires a closer look at these contributing elements.
Incomplete removal: Sometimes, during the initial treatment, not all cancer cells can be completely removed. This can occur due to the tumor’s location, depth, or size, making complete excision challenging. As a result, residual cancer cells may persist and eventually lead to a recurrence.
Aggressive tumor characteristics: Certain characteristics of the tumor itself can contribute to the likelihood of recurrence. These features include deep invasion of the dermis, perineural invasion, lymphatic involvement, or presence of satellite nodules. Tumors with these aggressive traits have an increased tendency to grow back even after treatment.
Underlying genetic mutations: Genetic mutations play a significant role in the development and progression of squamous cell carcinoma. In some cases, these mutations can lead to treatment resistance, promoting the recurrence of the cancer. Additionally, certain genetic factors may influence the aggressiveness and invasiveness of the tumor cells, making them more likely to come back.
Dr. Emily T. Wong, a dermatologist, explains the challenges of squamous cell carcinoma recurrence, stating, “The recurrence of squamous cell carcinoma can be partly attributed to incomplete removal during treatment. Additionally, aggressive tumor characteristics and underlying genetic mutations may contribute to its persistence.”
Interesting facts about squamous cell carcinoma and its recurrence:
- Squamous cell carcinoma accounts for approximately 20% of all skin cancers.
- Prolonged sun exposure, radiation therapy, chemicals, and immunosuppression are known risk factors for squamous cell carcinoma.
- Squamous cell carcinoma can develop on various areas of the skin, including the head, neck, lips, back of the hands, and genital areas.
- While most squamous cell carcinomas are localized and have a good prognosis, some cases can metastasize to regional lymph nodes or distant organs.
- Regular check-ups and diligent self-examination of the skin can aid in early detection and improved outcomes.
Here’s a table presenting the contributing factors to squamous cell carcinoma recurrence:
|Incomplete removal||Not all cancer cells are removed during treatment, leading to the persistence of the disease.|
|Aggressive tumor characteristics||Certain features of the tumor make it more likely to recur, such as depth of invasion or lymphatic involvement.|
|Underlying genetic mutations||Genetic mutations can promote cancer recurrence and resistance to treatment.|
In conclusion, the recurrence of squamous cell carcinoma can be attributed to various factors such as incomplete removal, aggressive tumor characteristics, and underlying genetic mutations. As ongoing research aims to understand and overcome these challenges, early detection, proper treatment, and regular monitoring remain critical in managing and reducing the likelihood of cancer recurrence.
I found further information on the Internet
That’s because individuals who were diagnosed and treated for a squamous cell skin lesion have an increased risk of developing a second lesion in the same location or a nearby skin area. Most recurrent lesions develop within two years after the completion of treatment to remove or destroy the initial cancer.
Squamous cell cancers on the nose, ears and lips are the most likely to come back. If you had treatment for a squamous cell skin cancer, you should see your doctor every 3 to 6 months for several years to check for recurrence.
Squamous cell carcinoma is a type of skin cancer caused by an overproduction of squamous cells in your epidermis, the top layer of your skin. Exposing your skin to the sun’s UV rays puts you at a high risk of getting skin cancer. Treatment to remove cancer leads to a positive prognosis if the cancer is found and treated early.
These include: The location of the initial lesion – Squamous cell carcinomas that develop on the ears, nose and lips are particularly prone to recurrence and should be monitored carefully after treatment. Actinic keratoses – These crusty skin growths result from damage caused by exposure to UV radiation.
Squamous cell carcinoma is considered a slow-growing cancer, and staging is not always necessary since the disease is often diagnosed before it has spread. Basal cell carcinoma, which is a more common type of skin cancer, rarely spreads and is often not staged because the tumor is removed before staging is necessary.
Video answer to your question
The video titled “What is Squamous Cell Cancer? – Squamous Cell Cancer Explained  [Dermatology]” explains that squamous cell cancers are the second most common type of skin cancer, caused by long-term sun exposure and individual genetics. The speaker stresses the importance of limiting sun exposure and protecting the skin. Treatment options include excision, Mohs surgery, and superficial radiation therapy. Regular visits to the dermatologist are crucial, as having one skin cancer increases the risk of developing more.