Platform

Therapy where it’s needed

Neuroparticle^TM Platform for Image-Guided Non-Invasive Brain Delivery of Magnetic Particles.

The Neuroparticle team has developed the Neuroparticle^TM platform based on expertise in MRI imaging, materials science and drug development. The Neuroparticle^TM platform enables a wide range of product applications to provide medicine directly to diseased tissues that are not accessible with conventional therapeutic approaches.  Neuroparticle is initially applying this proprietary platform to create therapies that directly target ear, nose and throat (ENT) diseases. Company’s long-term goal is to use its technology to serve as a non-invasive alternative to brain cancer and other brain diseases that are primarily limited by the invasiveness of the procedure.

The Neuroparticle^TM platform is comprised of two technology components 

1. A novel compact MRI which can propel the microscopic devices under real-time imaging guidance

• • Head sized,
  • High resolution
  • Low field
  • Portable
  • No shielding
  • No cooling
  • Low cost
  • Capable of manipulating magnetic particles
  • Image anatomy and particles in real time
  • Actuate particle drilling, heating
  • Monitor treatment

2. A novel compact MRI which can propel the microscopic devices under real-time imaging guidance

• • Single-use shape-engineered mission-specific microscopic magnetic devices
  • Highly-uniform microscopic particles
  • Pre-programmed biodegradability
  • Can be focally concentrated
  • Drill through tissue without damage
  • Can deliver drug or gene payloads
  • Can image particles and anatomy together
  • Bypasses blood-brain barrier
  • Non-invasively pushes particles into and through brain
  • Enables tunable drug elution for long-term dosing
  • Can thermally ablate solid tumors
  • Can concentrate drug, cell or gene products to a specific and targeted location
  • Can elute drug products
  • Has features that enable quick rotation to break biofilm, drill through tissue
  • Particle-drug complex can be customized for many disease

Proprietary Technology Platform

Neuroparticle^TM has a robust global portfolio of intellectual property. These patents cover all aspects of the MRI and particle including

• Comfortable high magnetic gradients
• MRI Particle focus
• Particle drilling
• Real-time imaging guidance
• Particle and system manufacturing methods
• Liquid crystal particles
• Electro-permanent low-power MRI
• Denoising

All intellectual property protecting the Neuroparticle^TM platform has been developed and is owned by the company.